Dr Moirangthem Dinesh Singh

DR. MOIRANGTHEM DINESH SINGH

Dr Moirangthem Dinesh Singh

Dr Moirangthem Dinesh Singh

Assistant Professor

Qualification:

Bachelor’s Degree: Microbiology, Zoology and Chemistry; Bangalore University, India
Master’s Degree: Biotechnology; Bangalore University, India
Ph.D.: Department of Biotechnology, Gauhati University, India
Other: UGC-NET (Life Sciences), Post-Doctoral Fellow, National Centre for Cell Science (NCCS) Pune, INDIA

Areas of Specialization:

  • Search for Potential Compounds of Natural Origin
  • Microbial Research and Food Safety
  • Traditional Medicine and Ethnopharmacology
  • Molecular and Cell Biology
  • Anti-neoplastic Drug Combination

Sl No

Title/Subject of Research Project

PI/Co-PI

Year of Commencement

Year of Completion

Sponsoring/
Funding Agency

1

Exploration of combination therapy of pelargonidin, a dietary anthocyanidin with cisplatin for treatment of small cell human lung cancer

PI

2025

2026

(Ongoing)

Department of Science and Technology, Government of Manipur

2

Quantifying the microbial risk in protein rich fermented foods of Manipur to identify the critical control points and development of LAMP based rapid diagnostic kit for major foodborne pathogens

Co-PI

2017

2020

Indian Council of Medical Research (ICMR)

  1. Surbala L, Babycha L, Moirangthem DS. Berberine enhances cisplatin sensitivity in non-small cell lung cancer H1299 cells via modulation of the p38-MAPK signaling pathway. Journal of Biologically Active Products from Nature. 2025, 15, 222–233. Impact factor – 1
  2. Moirangthem DS, Laishram S. Remdesivir (GS-5734) in COVID-19 therapy: the fourth chance. Current Drug Targets. 2021, 22, 1-12. Impact factor – 2.937
  3. Shantabi L, Jagetia GC, Moirangthem DS, Nongalleima K. Anticancer activity of an ethnomedicinal plant Croton caudatus Geiseler, Kam sabut in cultured HeLa cells. Biocatalysis and Agricultural Biotechnology. 2020, 23, 101500, 1-9. Impact Factor- 3.8.
  4. Laishram S, Moirangthem DS, Borah JC, Pal BC, Suman P, Gupta SK, Kalita MC, Talukdar NC. Chrysin rich Scutellaria discolor induces cervical cancer cell death via the induction of cell cycle arrest and caspase-dependent apoptosis. Life Sciences. 2015,143,105–113. Equal Contributor. Impact factor – 6.78
  5. Moirangthem DS, Laishram S, Rana VS, Borah JC, Kalita MC, Talukdar NC. Essential oil of Cephalotaxus griffithii needle inhibits proliferation and migration of human cervical cancer cells: Involvement of mitochondria-initiated and death receptor-mediated apoptosis pathways. Natural Product Research. 2015, 29, 1161-1165. Impact factor – 2.488.
  6. Deb L, Laishram S, Khumukcham N, Dey A, Moirangthem DS, Talukdar NC, Tombiraj N. Talukdar NC, Ningthoukhongjam TR. Past, present and perspectives of Manipur Traditional Medicine: A major health care system available for rural population in the North -East India. Journal of Ethnopharmcology. 2015, 169, 387-400. Impact factor – 5.195.
  7. Laishram S, Sheikh Y, Moirangthem DS, Deb L, Pal BC, Talukdar NC, Borah JC. Anti-diabetic molecules from Cycas pectinata traditionally used by the Maiba-Maibi. Phytomedicine. 2014, 22, 23–26. Impact factor – 6.656.
  8. Buragohain P, Surineni N, Barua NC, Bhuyan PD, Boruah P, Borah J, Laishram S, Moirangthem DS. Synthesis of a novel series of Fluoroarene derivatives of Artemisinin as potent antifungal and anticancer agent. Bioorganic and Medicinal Chemistry Letters. 2015, 25, 3338-3341. Impact factor – 2.94.
  9. Moirangthem DS, Laishram S, Borah JC, Kalita MC, Talukdar NC. Cephalotaxus griffithiif. needle extract induces cell cycle arrest, apoptosis and suppression of hTERT and hTR expression on human breast cancer cells. BMC Complementary and Alternative Medicine. 2014, 14, 1-10. Impact factor – 2.838.
  10. Moirangthem DS, Borah JC, Laishram S, Kalita MC, Talukdar NC. HPLC analysis of harringtonine and homoharringtonine in the needles of Cephalotaxus griffithii alkaloid fraction and cytotoxic activity on chronic myelogenous leukaemia K562 cell. Natural Product Research. 2014, 28, 1-4. Impact factor – 2.488.
  11. Devi AB, Moirangthem DS, Talukdar NC, Devi MD, Singh NR, Luwang MN. Novel Synthesis and Characterisation of CuO Nanomaterials: Biological Applications. Chinese Chemical Letters. 2014, 25, 1615-1619. Impact factor – 8.455.
  12. Moirangthem DS, Talukdar NC, Bora U, Kasoju N, Das RK. Differential effects of Oroxylum indicum bark extracts: Antioxidant, antimicrobial, cytotoxic and apoptotic study. Cytotechnology. 2013, 65, 83-95. Impact factor – 2.04.
  13. Moirangthem DS, Talukdar NC, Kasoju N, Bora U. Antioxidant, antibacterial, cytotoxic, and apoptotic activity of stem bark extracts of Cephalotaxus griffithii Hook. F. BMC Complementary and Alternative Medicine. 2012, 12, 1-10. Impact factor – 2.838.

1. Co-ordinator, Research and Development, Manipur Technical University.
2. Member, Board of Studies (BoS), Department of Basic Sciences (Biological Sciences), Manipur Technical University.
3. Member, Board of Studies (BoS), Department of Basic Sciences (Chemistry),
Manipur Technical University.