Dr Moirangthem Dinesh Singh

Dr Moirangthem Dinesh Singh

Assistant Professor

Qualification:

Bachelor’s Degree: Microbiology, Zoology and Chemistry; Bangalore University, India
Master’s Degree: Biotechnology; Bangalore University, India
Ph.D.: Department of Biotechnology, Gauhati University, India
Other: UGC-NET (Life Sciences)

Areas of Specialization:

  • Search for potential compounds of natural origin
  • Anti-neoplastic Drug Combination
  • Metabolism
Sl no Title/Subject of Research Project PI/Co-PI Year of Commencement Year of Completion Sponsoring/ Funding Agency
1 Quantifying the microbial risk in protein rich fermented foods of Manipur to identify the critical control points and development of LAMP based rapid diagnostic kit for major foodborne pathogens Co-PI 2017 2020 Indian Council of Medical Research (ICMR)
  1. Moirangthem DS, Laishram S. Remdesivir (GS-5734) in COVID-19 therapy: the fourth chance. Current Drug Targets. 2021, 22, 1-12. Impact factor – 2.937.
  2. Shantabi L, Jagetia GC, Moirangthem DS, Nongalleima K. Anticancer activity of an ethnomedicinal plant Croton caudatus Geiseler, Kam sabut in cultured HeLa cells. Biocatalysis and Agricultural Biotechnology. 2020, 23, 101500, 1-9. Impact Factor- Yet to come.
  3. Laishram S, Moirangthem DS, Borah JC, Pal BC, Suman P, Gupta SK, Kalita MC, Talukdar NC. Chrysin rich Scutellaria discolor induces cervical cancer cell death via the induction of cell cycle arrest and caspase-dependent apoptosis. Life Sciences. 2015,143,105–113. Equal Contributor. Impact factor – 6.78
  4. Moirangthem DS, Laishram S, Rana VS, Borah JC, Kalita MC, Talukdar NC. Essential oil of Cephalotaxus griffithii needle inhibits proliferation and migration of human cervical cancer cells: Involvement of mitochondria-initiated and death receptor-mediated apoptosis pathways. Natural Product Research. 2015, 29, 1161-1165. Impact factor – 2.488.
  5. Deb L, Laishram S, Khumukcham N, Dey A, Moirangthem DS, Talukdar NC, Tombiraj N. Talukdar NC, Ningthoukhongjam TR. Past, present and perspectives of Manipur Traditional Medicine: A major health care system available for rural population in the North -East India. Journal of Ethnopharmcology. 2015, 169, 387-400. Impact factor – 5.195.
  6. Laishram S, Sheikh Y, Moirangthem DS, Deb L, Pal BC, Talukdar NC, Borah JC. Anti-diabetic molecules from Cycas pectinata traditionally used by the Maiba-Maibi. Phytomedicine. 2014, 22, 23–26. Impact factor – 6.656.
  7. Buragohain P, Surineni N, Barua NC, Bhuyan PD, Boruah P, Borah J, Laishram S, Moirangthem DS. Synthesis of a novel series of Fluoroarene derivatives of Artemisinin as potent antifungal and anticancer agent. Bioorganic and Medicinal Chemistry Letters. 2015, 25, 3338-3341. Impact factor – 2.94.
  8. Moirangthem DS, Laishram S, Borah JC, Kalita MC, Talukdar NC. Cephalotaxus griffithiif. needle extract induces cell cycle arrest, apoptosis and suppression of hTERT and hTR expression on human breast cancer cells. BMC Complementary and Alternative Medicine. 2014, 14, 1-10. Impact factor – 2.838.
  9. Moirangthem DS, Borah JC, Laishram S, Kalita MC, Talukdar NC. HPLC analysis of harringtonine and homoharringtonine in the needles of Cephalotaxus griffithii alkaloid fraction and cytotoxic activity on chronic myelogenous leukaemia K562 cell. Natural Product Research. 2014, 28, 1-4. Impact factor – 2.488.
  10. Devi AB, Moirangthem DS, Talukdar NC, Devi MD, Singh NR, Luwang MN. Novel Synthesis and Characterisation of CuO Nanomaterials: Biological Applications. Chinese Chemical Letters. 2014, 25, 1615-1619. Impact factor – 8.455.
  11. Moirangthem DS, Talukdar NC, Bora U, Kasoju N, Das RK. Differential effects of Oroxylum indicum bark extracts: Antioxidant, antimicrobial, cytotoxic and apoptotic study. Cytotechnology. 2013, 65, 83-95. Impact factor – 2.04.
  12. Moirangthem DS, Talukdar NC, Kasoju N, Bora U. Antioxidant, antibacterial, cytotoxic, and apoptotic activity of stem bark extracts of Cephalotaxus griffithii Hook. F. BMC Complementary and Alternative Medicine. 2012, 12, 1-10. Impact factor – 2.838.